What is post-thrombotic syndrome?

Post-thrombotic syndrome (PTS) is a problem that can happen after you've had a deep vein blood clot, called deep vein thrombosis (DVT). After a while, this blood clot (usually in your leg) can cause the pressure in your vein to rise. This pressure can damage the vein. PTS is also called postphlebitic syndrome.

Veins have valves that keep the blood moving in one direction—toward the heart. With PTS, the valves in a damaged vein may not work well. Some blood may leak backward through the valve. PTS can cause long-term problems such as swelling, skin damage, and painful sores (venous skin ulcers) near the ankle.

PTS can be a long-term problem that lasts for years.

Symptoms of post-thrombotic syndrome include:

• Pain, discomfort, swelling, or itching.
• Slow-healing sores.
• Brownish discoloration or darkening of the skin.
• Fragile skin on the area, which bruises easily. The skin may be dry and may peel.

Your doctor will probably be able to diagnose PTS from your medical history, your symptoms, and a physical exam. You might have an ultrasound test so your doctor can check blood flow in your veins.

You may need to wear specially fitted compression stockings to treat post-thrombotic syndrome (PTS). You may need to use an intermittent pneumatic compression device. These devices inflate and deflate knee-high boots. These stockings and devices may help with pain and swelling. If you have sores, you may need medicines and bandages to help the sores heal.

Propping up your leg may reduce pain and swelling.

You might try an exercise program to help relieve PTS symptoms. Talk with your doctor before starting a new exercise program. Your doctor might recommend strength training for your legs and aerobic exercise, such as walking.

For people who have severe symptoms and have a risk of serious problems, surgery or a catheter procedure might be done to restore blood flow. These procedures are not commonly done.

There are things you can do. Be active. Avoid sitting or standing for long periods. Prop up your legs when you sit or lie down. Stay at a weight that's healthy for you. Treat cuts and scrapes on your legs right away. Keep your legs clean and moisturized.